What do you always have in your handbag?

Always?
No keys: we don't lock our home, and since we share a car the key lives in a drawer.
No wallet: I forget it at home several times a year.
No make-up: I never wear any.
Random scraps of paper with illegible notes it is, then.

Other than the obvious stuff to get around with, I always keep a colored lip balm, small mirror, spare toothpicks, hair ties, hand sanitizer, ear buds, and a pen. :)
In a bigger bag, I’ll throw in a hat, sunglasses, and a tote bag for grocery shopping.

Hairbrush, zipper wallet with cards and a little bit of cash for emergencies, a small bottle of perfume (Victoria’s Secret Coconut Passion, my partner got it as a gift in 2013 and never used it lol), phone cable and sometimes a battery bank, pack of travel tissues, a pill bottle with 2 days of my ADHD meds in case I forgot to take them, a few cotton buds for if my eyeliner transfers to the lower lid, a few cotton pads for cleaning up any cakey looking makeup or runs from being too warm, tinted lip balm, lip gloss, a reusable shopping bag, a travel umbrella, and the apartment keys.
Might need a Bag of Holding tbh.
- You are a regular Mary Poppins! You're super organised I approve
  
  A year or so ago I bought a nice handbag that came with a smaller removable bag on the inside that I keep everything in. It sure makes changing bags easier since every handbag I own can accommodate that smaller bag 🤣
  Forgot to mention that inside the wallet there is also a few doses of paracetamol and ibuprofen for headaches as well as cetirizine for allergies. My partner loves the fact that I have her covered in case of emergency ☺️

Intentional: pack of tissues, lip balm, tampons, pen, packet of oatcakes, Loop earbuds, headphones, purse, keys, hair ties
Unintentional: old receipts, old tissues, oatcake crumbs
Occasional: notebook, book to read, shopping bag
- I approve of the emergency snacks. This is important
- I should really add an emergency snack. Smart!

My keys, purse + credit card, ID, hand sanitizer + mask
- Are many people still using masks in Canada? It's unheard of in the UK now
  
  Uncommon in my area, but I've made it a permanent habit since 2020. I'd hate to make anyone else sick!

I always have a refillable bottle of water, my purse, keys, at least one lipbalm, a few receipts for random things and a miscellaneous item I don't remember putting in it. There's often a biro in there, despite the fact that I swear I never put birds in it!

Since I'm on a motorbike most of the time I use a backpack, which in and of itself has proved useful!
Inside I've got ... Work ID Old leather purse I bought second hand about 15 years ago Antihistamines Ibuprofen Mini hairbrush Mini nailclippers A reliable pen Hand sanisizer House keys 1 individually wrapped maxi-pad (useful for various emergencies aside from the obvious) 1 pair of disposable earplugs (for when riding the motorbike) And the most recent addition is reading glasses :-(
- Motorbike is impressive! How long have you had it?
  
  It's funny, here in Spain there's lots of women who use motorbikes and scooters as their main transportation so I've never thought of it as impressive!
  I've had motorbikes since I was little, I was fascinated by them much to my mothers disappointment.
  Have you ever thought about riding one?

Mine has a reusable face mask, keys, wallet, collapsible brush, pocket knife, lip balm, a stainless steel mirror in a cover and some loose change and there's pepper spray clipped to the outside. Depending on where I am going and the time of day also a small pistol.
I noticed you mentioned masks in another comment; I wear my mask when i go in healthcare settings or any place folks might be breathing on me. Lots of shopkeepers here still wear them.
I just realized i should throw a couple band-aids in there!
- Have you been shooting long? I went shooting in America a few years ago and LOVED it
  
  I have been shooting about 30 years now, throwing lead is fun.

Wallet, mask, keys, mini scissors, dog poo bags, my meds, Loop ear plugs
My partner's very covid-cautious and we both have immuno-compromised friends, so we both mask in stores or other crowded places.

My main bag is an old sling bag with keys, wallet, phone, hair ties, pens (four colour bic, sharpie, and fountain), vape, folded up shopping bag, rolaids, mini tape measure, two crystals, headphones, fisherman’s friends, vape coil, nicotine patch, vape juice, protein bar. And two lip balms that I never use. And my leatherman would be in there too if I hadn’t of lost it!
This bag goes in a larger bag that holds water bottle, travel mug, planner, iPad, kobo, little toiletry bag (pill bottle (melatonin, ibuprofen, Tylenol, Benadryl, adhd meds), tampon, pads, menstrual cup, tea bags, lighter, emergen-c, hair ties, vape coils, nicotine patches), big headphones, spare vape, protein bar, sunglasses
Sometimes that bag will go in a larger bag (like a basket) to hold other extra stuff, like lunch (in its own bag), vitamins, snacks, extra books. I sorted it all out like Russian nesting bags haha. I travel for work so switch things up a lot, and with everything in its own place I don’t forget stuff. If I’m just running in the store then I grab the sling, if I’m heading into work, then next bag up. If I need a backpack I can move stuff around easy.
I have a separate backpack/bag for my laptop, work binders, and tech bag. The tech bag has a ton of pockets and holds all the different cables, wall wart, usb mouse, hard drive, usb hub, extra headphones, adapters, sd cards, pens, business cards, and ferry tickets. I love that bag.
Yes I know I’m horribly addicted to nicotine. Also, I don’t care if someone goes in my bag(s), provided I know they’re doing it of course.
Edit: after reading more of the responses to the question I have to say, this is mainly because I travel so much, and I happen to be on the road right now. If I was at home it would be just the sling!
- Seems like you are always ready to roll!
  When would you prefer to use the fountain pen?
  
  I like to be prepared!! The fountain pen gets used mostly for writing in my planner, or little sketches. TBH, I don’t use it as much as the bic though. It’s ridiculous, but I don’t want to mess it up and I’m hard on things.
- I would LOVE to be friends with someone who carried this much. I'd know wherever we were we'd be totally covered. How do you keep it all organised?
  
  Bags with pockets haha. Seriously though, just having a bunch of small bags that are specific to what’s inside them. Then I can just grab the bags I need and off I go.
  I like being able to help someone if they need something, I don’t even use tampons or pads, but other people do.

Nothing. I don't carry a bag unless the weather is warm and my outfit doesn't have adequate pockets.
- Your username is brilliant I love it

pens
micellar water
makeup remover pads
4 or 5 qtips
dry shampoo
hair brush
nail file
cuticle oil
my 'google pixel pros' (wireless earbuds)
phone (if no pockets)
crayon eyeliner
eyelash curler
mascara
glasses alcohol wipes
lip gloss
chap stick
wallet
top coat polish
a little ibuprofen bottle
edit: on closer inspection, 4 different bottle tabs. I collect them :)
- That's an impressive haul!

Wallet, kindle, field notes, assorted pencils and pens, bandaids, measuring tape, knife, disposable and reusable earplugs, headphones, lip balm, masks, 1 reusable shopping bag, hair ties, tampons, hand sanitizer, dog poop bags, random mix of meds in one bottle, gloves, and a hat.

keys, wallet, pepper spray, stocked pill case, chapstick, reusable bag, tide pen, cuticle oil, nail file, earplugs, gum, masks, bandaids, pads, tampons, and a pen
ETA: hand sanitizer

Actually most of the time I have a lanyard that has my ID, 2 credit cards, insurance card, Costco card, and library card, plus my car keys.
In my purse I have a wallet that holds my checkbook, other cards, and cash if I have it. Then there’s chapstick and a pen.
I think that’s about it.