For here am I sitting in my tin can

Bone density loss, radiation exposure, extended recovery time post microgravity.

I'm sure they mind as much as all those things matter.

There are significant health complications that come with long term space travel.

• Bone density loss. From the lack of daily impact on the skeleton from walking, moving around, and lifting things.
• Loss of muscle mass, also from the lack of use. ISS residents need to adhere to a pretty strict workout regimen, and still have issues with significant muscle loss when they return to earth.
• Radiation exposure. The atmosphere protects us from a lot of radiation, simply due to the fact that air has mass, and is able to stop a lot of radioactive particles before they reach the surface. Airline flight crews (like pilots and attendants) are considered an increased radiation risk, because they spend so much time at high altitudes. It’s even worse in the ISS, where the only thing between them and radiation is some thin glass and aluminum.
• Loss of coordination. Returning to the surface is more disorienting the longer you have been in space. Basically, you get used to the way microgravity feels, and suddenly experiencing gravity again is a shock to your system. You’ll constantly drop things because you’re used to things just floating when you let go of them. You’ll fall over, because you’re not used to actively keeping yourself upright. The same way long-term respirator patients need to re-learn how to breathe after being taken off the machine, long-term microgravity means you need to re-learn how to exist in gravity.

Yes, because the movie is all about how easy it was and nothing goes wrong

They're not really in need of rescue though, they're on the ISS. Their return vehicle is just a pile of garbage. Thanks again, Boeing.

The joke is straightforward. 2 minute cold open of a quick adventure becoming a massive ordeal breaking them, making Rick say they need a vacation which the episode is about.

https://youtu.be/pMLIQP46OwE

Honestly, give it a watch and see if it's for you. Last I saw it was available to stream on Hulu (and uBlock Origin does a good job blocking Hulu's ads)

I found it enjoyable but I don't have a strong need to rewatch it. It's raunchy and absurdist, but does some cool SciFi things I haven't seen elsewhere. But it's way less deep and intellectual than some of its stans seem to think

First season is decent but contains a lot of piss/fart/burp jokes; it calms down a bit afterwards. The really best seasons are 4 and onwards.

It’s fun to watch if you’re not too easily offended and like the genre.

It got a LOT better in later seasons

I watched the very first episode, it was pretty bad. Also the fan base are awful.