Acoustic? You'd need something lively and familiar. A great option for country music is "friends in low places". Oldies, "hound dog" can get a party bouncing. More modern pop, something like cee-lo green's "fuck you" would work okay (there's tabs for it, and I've heard it done on acoustic, and it did get a crowd going).
Electric, it's way too open, but that's more of a party killer because it's just too loud for small settings and good conversation, which is what actually makes a home party fun. If you wanted loud music, you'd play stuff on a stereo rather than have one guitarist noodling and fucking around (and they will noodle and fuck around, guitarists can't help it).
So, it's really about the crowd, in other words. Unless the crowd is musically homogeneous, you gotta go with famous songs that cross genres because of the popularity.