Nah, it's a very faithful remake - after a lot of back-and-forth of them considering changing the game more they ended up making a near 1-to-1 graphics update.
So I would recommend it. There are some parts that are made more challenging. Inventory management is a big one. OTOH that makes sense, as the modern controls enable *far more accurate combat and hence saving ammo is somewhat easy and you can easily use the shotgun or the magnum as staples.
I basically saved teflon ammo whenever I found it (dumped it all near the cargo lift) then before entering level 8 retrieved my modded Scorpion from there with nearly 1500 ammo and just went to town with that + leftover shotgun shells. But the drops are also changed, so both teflon bullets and magnesium ones for the Assault Rifle still commonly drop in the final few areas.
And of course, taken from the main game, EMP grenade into berserk-stim Laser Rapier is always an option and kills even the toughest enemies in the game before they recover.
That being said, one specific thing is annoying: Beta grove now deals constant and quite significant damage even with the enviropack on. You have to rush rush rush it, luckily it is brief. Other than that, it's neatly improved, modern graphics with a cool retro-effect from the nearest-neighbor filter, modern controls and combat and some better and more convenient HUD, redone audio including new recordings from Terri Brosius (SHODAN), they also completely redid cyberspace. While I like the original, I can see why most did not, so I really don't mind this part.