The steam version tries to implement keyboard shortcuts as much as possible. Alot of 'buttons' will show the keyboard shortcuts when you hover over them. The ASCII version is keyboard shortcut heaven and hell.
There are so many interacting systems running under the hood that you won't be aware of (ie, the famous 'bug' that was killing cats). Play until one them kills you, then play again to see a different one kill you in an unexpected and fascinating way. Losing is fun.
They're currently working on getting the adventure mode implemented into the steam version that I'm really looking forward to.
The community is great and if you can't figure something out, like how to make soap, there's probably a detailed wiki and a several year long running story that someone still updates detailing how to do it and how it all went wrong and killed everyone.
RimWorld is very good, not as complicated, and much more mouse heavy.