Calls for defederation - Is the idea of the open marketplace of ideas outdated?

Lately I see a lot of calls do have specific instances defederated for a particular subset of reasons:

• Don't like their content
• Dont like their political leaning
• Dont like their free speech approach
• General feeling of being offended
• I want a safe space!
• This instance if hurting vulnerable people

I personally find each and every one of these arguments invalid. Everybody has the right to live in an echo chamber, but mandating it for everyone else is something that goes a bit too far.

Has humanity really developed into a situation where words and thoughts are more hurtful than sticks and stones?

Edit: Original context https://slrpnk.net/post/554148

Controversial topic, feel free to discuss!