I'm 3/4s through my second playthrough and appreciating it more and more. Haven't picked up the expansion yet either.
I found it hits much harder with a female character. The Johnny Silverhand situation especially felt much more... metaphorically resonant? And Jackie feels more rogue-with-a-heart-of-gold when his best buddy is a woman.
Quickhacks are OP but felt correctly haxx0r, mantis blades are super fun. I enjoyed the combat well enough. Cars are meh, but it's cyberpunk so if you're not riding a futuristic bike ala Akira you're doing it wrong. And wiping out on a bike is great.
The characterisation and world building are what really shine. I was reluctant to play the corpo background but it really makes the story sing.