I just recently tried a game running with proton (which i understand is wine with extras). I was really impressed cause i download it and it was just running. Maybe i got lucky or it was just the game (valheim).
My only big trouble with all of this is the hardware management, not having access to software like adrenaline gives me a bad feeling. I ran the game steadily with the GPU at around 60°C, but certain situations, and specially the "start up" produced peaks of 90°C in really small time windows. Thats holding me for now.
As I understand, valheim has a linux native version but i wamted to try proton after all.