Rip Teddit

Reddit front-ends access Reddit data in a way that is now bound by much stricter rate-limiting than ever before.
Popular instances may be usable for a short time until their limit is reached, then they will 429 like everyone else.
If you, personally, host a Reddit front-end instance, you are still affected, you are just less likely to reach the limit as quickly as public instances.

Here's what the Libreddit project intends to do about it: https://github.com/libreddit/libreddit/issues/836
If similar projects plan to continue, they will likely follow a similar approach.