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That's just the single most obvious out of dozens of differences. Do you prefer fifty checkboxes or one dropdown list? Here's a better way to look at this: medication cares about your biology. That means sex. Gender does not factor in. So they're asking your sex. Why would they need to know your gender? Wouldn't asking that be invasive, like asking your political affiliation or your hobbies or your religion or literally anything else that does not impact your purchase and use of medicine?

Transphobia