I think many men, whether they realize it or not, feel specifically persecuted by trans rights. They might say that allowing trans women in women’s sports is cheating and that it would allow the trans women to be successful in the sport over less merit than they as cis males would have to. The deconstruction of the gender/sex binary also threatens cis males’ historic position as self-assigned protectors, leaders, and winners of the “weaker sex”. There is also the phobia among men of discovering that the woman whom they want to romance is trans, which really comes down to masculine fragility and conformity that leads to homophobia (in the sense of XY + XY, not gender) and transphobia. As a cis male, these men need to get over themselves.
Many men also believe that gun control is a threat to them. They need these guns in case a fascist power ever seizes the government and they need to fight back, so they are actively voting for the fascist powers to seize the government so that they can keep their guns.
There are also men who hold prejudice against any religion except Christianity so leftwing inclusivity efforts and anti-prejudice efforts come across as welcoming these perceived threats. These men aren’t simply just the redneck Bible thumpers or even devout or practicing Christians, but they just see the most common belief system around them as the default.
It’s not that these issues are a threat to men, but that they perceive them as threats.