Resident Evil Director's Cut on PS1. I was fairly young and not very good at the "survival" aspect of the survival horror. I tried to kill everything I encountered and consumed copious amounts of ammo and herbs doing so. I reached a place where I had a single ink ribbon left, no ammo, health on the red, and confused on where I needed to go next. And I had to go do homework. So I used my last ribbon and saved.
I discovered next time I played that the way forward was through a tight corridor I missed filled with zombies who could now one-shot me. I tried and tried and literally was unable to get through. First time I ever learned the word "soft-locked" as my brother wheezed it out while laughing. Good times!