I tried wine recently to see if I can get Total Annihilation to work. I played with Wine in the mid 2000's and gotten office 2003 to run on Suse then.
OMFG the mess when I recently tried to just run a simple exe that doesn't even need a full installation.
Adobe sadly don't just make Photoshop which is a remarkably good product. Even more so with their new features. I use Lightroom and nothing that exists for Linux comes close. All that needs some serious GPU integration.
DaVinci resolve is amazing and a real alternative to Premiere.
The problem I see is binary compatibility.
Even Linus admits that the Linux desktop has a problem with that.
I do have high hopes for web tech to evolve enough to make cross platform a thing again. Maybe ChromeOS will help there. VS Code is a good example here. With WebGl Vulkan in the browser and OpenCL that should become viable soon.