I keep both the 4 hour and the 12 hour time-released versions at home. There's no substitute. I'll gladly spend a few extra minutes at the pharmacy counter to obtain it.
Maybe I'm a lightweight, but pseudoephedrine makes me feel weird. I can't put my finger on it, but maybe a bit jittery and kind of cold. Also hyper - like I'll want to do chores when I take it
Works better than anything else for my colds, but it also makes me feel odd so I avoid it unless I'm feeling super trash.