Anything I run on Proxmox, per my own requirements, needs to be hardware-agnostic. I have a 3-node cluster set up to be a "playground" of sorts, and I like being able to migrate VMs/LXCs between different nodes as I see fit (maintenance reasons or whatever).
Some services I want to run on their own hardware, like Home Assistant, because it offers more granular control. The Lenovo M710q Tiny that my HA system runs on, even with its i7-7700T, pulls a whopping 10W on average. I'll probably change it to the Pentium G4560T that's currently sitting on my desk, and repurpose the i7-7700T for another machine that could use the horsepower.
My NAS is where Im more concerned about separation of duties. I want my NAS to only be a NAS. OMV is pretty simple to manage, has a great dashboard, spits out SMART data, and also runs a weekly rsync backup command on my RAID to a separate 8TB backup drive. I'm currently in the process of building a "new" NAS inside a gutted HP server case from 2003 to replace the Mac mini/USB 4-bay drive enclosure. New NAS will have a proper HBA to handle drives.
or is there some other dragon awaiting me (aside from the power bills after I switch over)?
My entire homelab runs about 90-130W. It's pulled a total of ~482kWh since February (when I started monitoring it). That's 3x tiny/mini/micro PCs (HP 800 G3 i7, HP 800 G4 i7, Lenovo M710q i7), an SFF (Optiplex 7050 i7), 2014 Mac mini (i5)/loaded 4-bay HDD enclosure/8TB USB HDD, Raspberry Pi 0W, and an 8-port switch.